NG2 anticorps (AA 2247-2308)

N° du produit ABIN1724837

L’anticorps Souris Monoclonal anti-NG2 a été validé pour FACS et ELISA. Il convient pour détecter NG2 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour NG2 anticorps (AA 2247-2308) (ABIN1724837)

Antigène: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NG2 est non-conjugé

Application: Flow Cytometry (FACS), ELISA

Clone: 7G4E5

Détail du produit anti-NG2 anticorps

Épitope: AA 2247-2308

Fonction: CSPG4 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CSPG4 (AA: 2247-2308) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-NG2 (ABIN1724837)

Wang, Katayama, Wang, Yu, Favoino, Sakakura, Favole, Tsuchikawa, Silver, Watkins, Kageshita, Ferrone: "Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." dans: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).

Price, Colvin Wanshura, Yang, Carlson, Xiang, Li, Ferrone, Dudek, Turley, McCarthy: "CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma." dans: Pigment cell & melanoma research, Vol. 24, Issue 6, pp. 1148-57, (2011) (PubMed).

Détails sur NG2

Antigène: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Autre désignation: CSPG4

Sujet: A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

Poids moléculaire: 250.0 kDa

ID gène: 1464

UniProt: Q6UVK1

Pathways: Glycosaminoglycan Metabolic Process