RING1 anticorps (AA 79-263)
Aperçu rapide pour RING1 anticorps (AA 79-263) (ABIN1724839)
Antigène
Voir toutes RING1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 79-263
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Fonction
- Ring1 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human Ring1 (AA: 79-263) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression." dans: The International journal of developmental biology, Vol. 53, Issue 2-3, pp. 355-70, (2009) (PubMed).
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: "Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression." dans: The International journal of developmental biology, Vol. 53, Issue 2-3, pp. 355-70, (2009) (PubMed).
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- RING1 (Ring Finger Protein 1 (RING1))
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Autre désignation
- Ring1
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Sujet
- This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.
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Poids moléculaire
- 42.4 kDa
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UniProt
- Q06587
Antigène
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