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Osteoactivin anticorps (AA 31-260)

GPNMB Reactivité: Humain WB, ELISA, IHC Hôte: Souris Monoclonal 7C10E5 unconjugated
N° du produit ABIN1724859
  • Antigène Voir toutes Osteoactivin (GPNMB) Anticorps
    Osteoactivin (GPNMB)
    Épitope
    • 15
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-260
    Reactivité
    • 60
    • 26
    • 25
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 48
    • 13
    Souris
    Clonalité
    • 49
    • 12
    Monoclonal
    Conjugué
    • 21
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Osteoactivin est non-conjugé
    Application
    • 48
    • 21
    • 13
    • 13
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. coli.
    Clone
    7C10E5
    Isotype
    IgG1
    Top Product
    Discover our top product GPNMB Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Tsui, Chang, Feng, Chang, Juang: "Glycoprotein transmembrane nmb: an androgen-downregulated gene attenuates cell invasion and tumorigenesis in prostate carcinoma cells." dans: The Prostate, Vol. 72, Issue 13, pp. 1431-42, (2012) (PubMed).

    Williams, Esmaeli, Soheili, Simantov, Gombos, Bedikian, Hwu: "GPNMB expression in uveal melanoma: a potential for targeted therapy." dans: Melanoma research, Vol. 20, Issue 3, pp. 184-90, (2010) (PubMed).

  • Antigène
    Osteoactivin (GPNMB)
    Autre désignation
    GPNMB (GPNMB Produits)
    Synonymes
    anticorps HGFIN, anticorps NMB, anticorps DC-HIL, anticorps Dchil, anticorps ipd, anticorps glycoprotein nmb, anticorps glycoprotein (transmembrane) nmb, anticorps glycoprotein nmb L homeolog, anticorps Gpnmb, anticorps GPNMB, anticorps gpnmb.L
    Sujet

    Description: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. ,

    Aliases: NMB, HGFIN

    Poids moléculaire
    64 kDa
    ID gène
    10457
    HGNC
    10457
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