Cet anticorps Souris Monoclonal détecte spécifiquement SERPINA7 dans ELISA. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.
Purified antibody in PBS with 0.05 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Yan, Yan, Ou: "Human thyroxine binding globulin (TBG) promoter directs efficient and sustaining transgene expression in liver-specific pattern." dans: Gene, Vol. 506, Issue 2, pp. 289-94, (2012) (PubMed).
Duhan, Patston: "Explanation for the high heat stability of thyroxine binding globulin-Chicago." dans: Endocrine regulations, Vol. 44, Issue 2, pp. 43-7, (2010) (PubMed).
Antigène
SERPINA7
(Serpin Family A Member 7 (SERPINA7))
Autre désignation
SERPINA7
Sujet
There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.