PAPLN anticorps (AA 766-870)

N° du produit ABIN1724896

Cet anticorps Souris Monoclonal détecte spécifiquement PAPLN dans ELISA, WB et ICC. Il présente une réactivité envers Humain et Souris et a été mentionné dans 2+ publications.

Aperçu rapide pour PAPLN anticorps (AA 766-870) (ABIN1724896)

Antigène: PAPLN (Papilin, Proteoglycan-Like Sulfated Glycoprotein (PAPLN))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAPLN est non-conjugé

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC)

Clone: 5B2E5

Détail du produit anti-PAPLN anticorps

Épitope: AA 766-870

Fonction: PAPLN Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PAPLN (AA: 766-870) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-PAPLN (ABIN1724896)

Fessler, Kramerova, Kramerov, Chen, Fessler: "Papilin, a novel component of basement membranes, in relation to ADAMTS metalloproteases and ECM development." dans: The international journal of biochemistry & cell biology, Vol. 36, Issue 6, pp. 1079-84, (2004) (PubMed).

Kramerova, Kawaguchi, Fessler, Nelson, Chen, Kramerov, Kusche-Gullberg, Kramer, Ackley, Sieron, Prockop, Fessler: "Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases." dans: Development (Cambridge, England), Vol. 127, Issue 24, pp. 5475-85, (2001) (PubMed).

Détails sur PAPLN

Antigène: PAPLN (Papilin, Proteoglycan-Like Sulfated Glycoprotein (PAPLN))

Autre désignation: PAPLN

Sujet: Papilin is an extracellular matrix glycoprotein involved in, thin matrix layers during gastrulation, matrix associated with wandering, phagocytic hemocytes, basement membranes and space-filling matrix during Drosophila development.Determination of its cDNA sequence led to the identification of Caenorhabditis and mammalian papilins. A distinctly conserved 'papilin cassette' of domains at the amino-end of papilins is also the carboxyl-end of the ADAMTS subgroup of secreted, matrix-associated metalloproteinases, this cassette contains one thrombospondin type 1 (TSR) domain, a specific cysteine-rich domain and several partial TSR domains. In vitro, papilin non-competitively inhibits procollagen N-proteinase, an ADAMTS metalloproteinase.

Poids moléculaire: 137.7 kDa

ID gène: 89932

UniProt: O95428