RING1 anticorps (AA 79-263)

N° du produit ABIN1724897

L’anticorps Souris Monoclonal anti-RING1 a été validé pour ELISA et ICC. Il convient pour détecter RING1 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour RING1 anticorps (AA 79-263) (ABIN1724897)

Antigène: RING1 (Ring Finger Protein 1 (RING1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RING1 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC)

Clone: 8E8A2

Détail du produit anti-RING1 anticorps

Épitope: AA 79-263

Fonction: Ring1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human Ring1 (AA: 79-263) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-RING1 (ABIN1724897)

Vidal: "Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression." dans: The International journal of developmental biology, Vol. 53, Issue 2-3, pp. 355-70, (2009) (PubMed).

Détails sur RING1

Antigène: RING1 (Ring Finger Protein 1 (RING1))

Autre désignation: Ring1

Sujet: This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

Poids moléculaire: 42.4 kDa

UniProt: Q06587