IGFBP7 anticorps (AA 52-156)

N° du produit ABIN1724903

L’anticorps Souris Monoclonal anti-IGFBP7 a été validé pour ELISA et IHC. Il convient pour détecter IGFBP7 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour IGFBP7 anticorps (AA 52-156) (ABIN1724903)

Antigène: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGFBP7 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 1D9E7

Détail du produit anti-IGFBP7 anticorps

Épitope: AA 52-156

Fonction: IGFBP7 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human IGFBP7 (AA: 52-156) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-IGFBP7 (ABIN1724903)

Evdokimova, Tognon, Benatar, Yang, Krutikov, Pollak, Sorensen, Seth: "IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors." dans: Science signaling, Vol. 5, Issue 255, pp. ra92, (2012) (PubMed).

Détails sur IGFBP7

Antigène: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Autre désignation: IGFBP7

Sujet: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).

Poids moléculaire: 29.1 kDa

UniProt: Q16270

Pathways: Growth Factor Binding