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GABBR2 anticorps (AA 319-483)

GABBR2 Reactivité: Humain WB, IHC, ELISA, ICC Hôte: Souris Monoclonal 5G7F7 unconjugated
N° du produit ABIN1724937
  • Antigène Voir toutes GABBR2 Anticorps
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    Épitope
    • 19
    • 15
    • 15
    • 15
    • 14
    • 13
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 319-483
    Reactivité
    • 89
    • 65
    • 59
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 105
    • 16
    Souris
    Clonalité
    • 97
    • 24
    Monoclonal
    Conjugué
    • 34
    • 10
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GABBR2 est non-conjugé
    Application
    • 113
    • 52
    • 52
    • 37
    • 32
    • 16
    • 16
    • 14
    • 13
    • 6
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human GABBR2 (AA: 319-483) expressed in E. coli.
    Clone
    5G7F7
    Isotype
    IgG2a
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Balasubramanian, Fam, Hall: "GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function." dans: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 4162-71, (2007) (PubMed).

  • Antigène
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    Autre désignation
    GABBR2 (GABBR2 Produits)
    Sujet

    Description: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence. , , , ,

    Aliases: HG20, GPR51, GPRC3B, GABABR2, HRIHFB2099

    Poids moléculaire
    105.8 kDa
    ID gène
    9568
    HGNC
    9568
    Pathways
    cAMP Metabolic Process
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