BMF anticorps (AA 2-14)
Aperçu rapide pour BMF anticorps (AA 2-14) (ABIN1732353)
Antigène
Voir toutes BMF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 2-14
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Specificité
- Reacts with the N-terminus part of human Bmf.
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Purification
- Purified
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Immunogène
- Peptide corresponding to aa 2-14 of human Bmf (accession no. NP_277038).
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Isotype
- IgG
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Indications d'application
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB (2 μg/mL) ICC (10 μg/mL) -
Restrictions
- For Research Use only
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Buffer
- PBS, pH 7.4
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Conseil sur la manipulation
- Dilute in PBS or medium that is identical to that used in the assay system.
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Stock
- -20 °C
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Stockage commentaire
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
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Date de péremption
- 12 months
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- BMF (Bcl2 Modifying Factor (BMF))
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Autre désignation
- Bmf
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Sujet
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In healthy cells, Bmf associates with the dynein light chain 2 component of the myosin V motors and is sequestered by the cell's actin cytoskeleton. Disruption of the actin cytoskeleton, either by depolymerization of actin filaments or by detachment of cells from the extracellular matrix, triggers release and activation of Bmf, initiating the downstream apoptotic program. Bmf is constitutively expressed in many tissues.
Bcl-2-modifying factor Bcl 2-modifying factor Gene name: BMF -
ID gène
- 90427
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UniProt
- Q96LC9
Antigène
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