ESRRA anticorps (N-Term)

N° du produit ABIN1734163

Cet anticorps Lapin Polyclonal détecte spécifiquement ESRRA dans WB et ICC. Il présente une réactivité envers Humain, Souris, Rat, Chien et Porc.

Aperçu rapide pour ESRRA anticorps (N-Term) (ABIN1734163)

Antigène: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reactivité: Humain, Souris, Rat, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESRRA est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Détail du produit anti-ESRRA anticorps

Épitope: AA 1-50, N-Term

Specificité: Reacts with human and mouse ESRRA protein

Réactivité croisée (Details): May cross react with rat, pig and dog (100 % sequence homology).

Purification: Purified

Immunogène: Synthetic peptide made to an N-terminal portion of the human protein (within residues 1-50). [Swiss-Prot# P11474]

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ICC : 1/100 - WB : 2.0 μg/mL

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, glycerol 30 % , Sodium azide 0.1 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 6 months

Détails sur ESRRA

Antigène: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Autre désignation: Estrogen-Related Receptor alpha (ERR-Alpha)

Sujet: Estrogen-related receptor alpha (ERR alpha) is an orphan member of the superfamily of nuclear hormone receptors. It was initially isolated based on its sequence homology to the estrogen receptor but is not activated by classic estrogens. ERR alpha preferentially binds to an ERR alpha response element (ERRE) containing a single consensus half-site, TNAAGGTCA. ERR alpha can control the expression of MCAD through the NRRE-1 and thus may play an important role in regulating cellular energy balance in vivo.

ID gène: 2101

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha