NOG anticorps (AA 156-170)
Aperçu rapide pour NOG anticorps (AA 156-170) (ABIN1737419)
Antigène
Voir toutes NOG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 156-170
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Specificité
- Reacts with Noggin from human, mouse and rat
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Purification
- Antigen affinity purified
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Immunogène
- Synthetic peptide comprising residues 156-170 [PVLYAWNDLGSRFWP] of the human Noggin protein
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Isotype
- IgG
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Indications d'application
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/1 000 to 1/2 000 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, Sodium azide 0.02 %
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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Date de péremption
- 6 months
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- NOG (Noggin (NOG))
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Autre désignation
- Noggin
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Sujet
- Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin, and 2) Noggin, which is a bone morphogenetic protein inhibitor.Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
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Pathways
- Stem Cell Maintenance, Tube Formation
Antigène
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