TP53INP1 anticorps (AA 1-14)
Aperçu rapide pour TP53INP1 anticorps (AA 1-14) (ABIN1737783)
Antigène
Voir toutes TP53INP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-14
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Specificité
- Reacts with human p53DINP1. Cross-reacts with mouse and rat protein.
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Purification
- Purified
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Immunogène
- Peptide corresponding to aa 1-14 of human p53DINP1. This sequence is identical in p53DINP1 alpha and beta and differs from that of mouse p53DINP1 by one amino acid.
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Isotype
- IgG
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Indications d'application
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Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB: 1-2 μg/mL
Positive control: Human lung tissue -
Restrictions
- For Research Use only
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Buffer
- PBS, pH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Dilute in PBS or medium which is identical to that used in the assay system.
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Stock
- -20 °C
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Stockage commentaire
- Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
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Date de péremption
- 6 months
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- TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
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Autre désignation
- p53DINP1
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Sujet
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Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response.
Tumor protein p53-inducible nuclear protein 1 Stress-induced protein p53-dependent damage-inducible nuclear protein 1, p53DINP1 Gene name: TP53INP1, P53DINP1, SIP -
ID gène
- 94241
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UniProt
- Q96A56
Antigène
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