PARK7/DJ1 anticorps (N-Term)
-
- Antigène Voir toutes PARK7/DJ1 (PARK7) Anticorps
- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
-
Épitope
- AA 167-189, N-Term
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PARK7/DJ1 est non-conjugé
-
Application
- Western Blotting (WB)
- Specificité
- Reacts with human and mouse PARK7. Sequence homology to mouse and rat DJ-1 is 82 % .
- Purification
- Purified
- Immunogène
- Synthetic peptide corresponding to amino acids 167-189 (AIVEALNGKEVAAQVKAPLVLKD) of human PARK7 conjugated to KLH at the N-terminus.
- Isotype
- IgG
- Top Product
- Discover our top product PARK7 Anticorps primaire
-
-
- Indications d'application
-
Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB1:500
Positive control: HEK293 cell lysate or mouse brain tissue lysate - Restrictions
- For Research Use only
-
- Buffer
- PBS, pH 7.4,
- Conseil sur la manipulation
- Dilute in PBS or medium which is identical to that used in the assay system.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
- Date de péremption
- 6 months
-
- Antigène
- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
- Autre désignation
- Park7 (PARK7 Produits)
- Synonymes
- anticorps DJ-1, anticorps DJ1, anticorps CAP1, anticorps Dj1, anticorps SP22, anticorps dj1, anticorps zgc:103725, anticorps park7b, anticorps park7, anticorps park7a, anticorps Parkinsonism associated deglycase, anticorps Parkinson disease (autosomal recessive, early onset) 7, anticorps parkinson protein 7, anticorps parkinson protein 7 S homeolog, anticorps parkinson protein 7 L homeolog, anticorps PARK7, anticorps Park7, anticorps park7, anticorps park7.S, anticorps park7.L
- Sujet
-
Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.
Protein DJ-1 Oncogene DJ1 Parkinson disease protein 7 Gene name: PARK7 - ID gène
- 11315
- UniProt
- Q99497
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
-