Neuroligin 3 anticorps (AA 730-848) (APC)

N° du produit ABIN1741459

Cet anticorps Souris Monoclonal détecte spécifiquement Neuroligin 3 dans WB, IHC, ICC et IF. Il présente une réactivité envers Rat.

Aperçu rapide pour Neuroligin 3 anticorps (AA 730-848) (APC) (ABIN1741459)

Antigène: Neuroligin 3 (NLGN3)

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuroligin 3 est conjugé à/à la APC

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: S110-29

Détail du produit anti-Neuroligin 3 anticorps (APC)

Épitope: AA 730-848

Specificité: Detects ~110 kDa. Does not cross-react with Neuroligin-1, -2, -4 or -4.

Réactivité croisée: Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3. Mouse: 99% identity (118/119 amino acids identical). Human: 98% identity (116/119 amino acids identical) ~60% identity with Neuroligin-1. ~40% identity with Neuroligin-2.

Isotype: IgG1

Information d'application

Indications d'application:

• WB (1:1000)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN1741459 was sufficient for detection of Neuroligin 3 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur Neuroligin 3

Antigène: Neuroligin 3 (NLGN3)

Autre désignation: Neuroligin 3

Sujet: Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses.

ID gène: 171297

UniProt: Q62889

Pathways: Synaptic Membrane