Complexin 1, 2 (AA 45-81) anticorps

N° du produit ABIN1742265

Cité dans 5 publications. Cet anticorps anti-Complexin 1, 2 Polyclonal Lapin (ABIN1742265) détecte spécifiquement Complexin 1, 2 dans ICC, IHC, IHC (p), IP et WB. L’anticorps est réactif avec des échantillons de Souris, Rat, Humain, Boeuf (Vache), Cobaye, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour Complexin 1, 2 (AA 45-81) anticorps (ABIN1742265)

Antigène: Complexin 1, 2

Reactivité: Souris, Rat, Humain, Boeuf (Vache), Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)

Classe de qualité: KO Validated

Détail du produit

Épitope: AA 45-81

Fonction: anti-Complexin1/2

Specificité: Recognizes complexin 1 and 2.

Réactivité croisée (Details): Reacts with: human (O14810, Q6PUV4), rat (P63041, P84087), mouse (P63040, P84086), Guinea pig, cow, zebrafish, rabbit. Other species not tested yet.

Purification: antiserum

Immunogène: Synthetic peptide corresponding to AA 45 to 81 from mouse Complexin2 (UniProt Id: P84086)

Information d'application

Indications d'application: WB:1 : 1000 up to 1 : 20000 ICC:1 : 200 up to 1 : 500, IHC:1 : 500, IHC-P:1 : 200,

Commentaires:

IP: Co-immunoprecipitates the SNARE complex.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

Conseil sur la manipulation: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Stock: -20 °C,4 °C

Stockage commentaire: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

Référence

Getz, Visser, Bell, Xu, Flynn, Zaidi, Syed: "Two proteolytic fragments of menin coordinate the nuclear transcription and postsynaptic clustering of neurotransmitter receptors during synaptogenesis between Lymnaea neurons." dans: Scientific reports, Vol. 6, pp. 31779, (2016) (PubMed).

Wilhelm, Mandad, Truckenbrodt, Kröhnert, Schäfer, Rammner, Koo, Claßen, Krauss, Haucke, Urlaub, Rizzoli: "Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins." dans: Science (New York, N.Y.), Vol. 344, Issue 6187, pp. 1023-8, (2014) (PubMed).

Tsai, Brewis, van Maaren, Gadella: "Involvement of complexin 2 in docking, locking and unlocking of different SNARE complexes during sperm capacitation and induced acrosomal exocytosis." dans: PLoS ONE, Vol. 7, Issue 3, pp. e32603, (2012) (PubMed).

Lee, Brecha: "Immunocytochemical evidence for SNARE protein-dependent transmitter release from guinea pig horizontal cells." dans: The European journal of neuroscience, Vol. 31, Issue 8, pp. 1388-401, (2010) (PubMed).

Falkowski, Thomas, Groblewski: "Complexin 2 modulates vesicle-associated membrane protein (VAMP) 2-regulated zymogen granule exocytosis in pancreatic acini." dans: The Journal of biological chemistry, Vol. 285, Issue 46, pp. 35558-66, (2010) (PubMed).

Détail du antigène

Antigène: Complexin 1, 2

Autre désignation: Complexin 1/2

Sujet: CPX 1, CPX1, CPX 2, CPX2, Synaphin-1, complexin 1, complexin 2, SNARE associated, eye-retina, 2

UniProt: P84086