Homer 1b/c (C-Term) anticorps

N° du produit ABIN1742339

L’anticorps Lapin Polyclonal anti- a été validé pour WB, ICC, IHC et IP. Il convient pour détecter dans des échantillons de Humain, Souris et Rat. Il y a 3+ publications disponibles.

Aperçu rapide pour Homer 1b/c (C-Term) anticorps (ABIN1742339)

Antigène: Homer 1b/c

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit

Épitope: C-Term

Fonction: Rabbit anti-Homer1b/c antibody

Specificité: Specific for homer 1b and 1c

Réactivité croisée (Details): Reacts with: human (Q86YM7-1), rat (Q9Z214-2, Q9Z214-1), mouse. Other species not tested yet.

Purification: affinity purified

Immunogène: Recombinant protein corresponding to the c-terminal half of human Homer 1b (UniProt Id: Q86YM7-1)

Information d'application

Indications d'application: WB:1 : 1000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Stock: -20 °C,-80 °C,4 °C

Stockage commentaire: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

Référence

Yoon, Piguel, Khalatyan, Dionisio, Savas, Penzes: "Homer1 promotes dendritic spine growth through ankyrin-G and its loss reshapes the synaptic proteome." dans: Molecular psychiatry, (2021) (PubMed).

Kim, Kong, Yamamoto, Kuramoto, Huang, Wang, Hong, Xiao, Levine, Qiu, Zhao, Miller, Dong, Meltzer, Xu, He: "An autophagy-related protein Becn2 regulates cocaine reward behaviors in the dopaminergic system." dans: Science advances, Vol. 7, Issue 8, (2021) (PubMed).

Tao-Cheng, Thein, Yang, Reese, Gallant: "Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation." dans: Neuroscience, Vol. 266, pp. 80-90, (2014) (PubMed).

Détail du antigène

Antigène: Homer 1b/c

Autre désignation: Homer1b/c

Sujet:

Synonyms: VesL 1, Syn47, Homer1 b, Homer1 c, Homer1 bc

Antigen Information: Homer1 , 2 and 3 are post synaptic density (PSD) proteins involved in the targeting of glutamate receptors

UniProt: Q86YM7