GFAP anticorps

N° du produit ABIN1742363

L’anticorps Lapin Polyclonal anti-GFAP a été validé pour WB, IHC, ICC, IP et IHC (p). Il convient pour détecter GFAP dans des échantillons de Humain, Rat, Souris, Poulet et Poisson zèbre (Danio rerio). Il y a 13+ publications disponibles.

Aperçu rapide pour GFAP anticorps (ABIN1742363)

Antigène: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reactivité: Humain, Rat, Souris, Poulet, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFAP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GFAP anticorps

Fonction: Rabbit anti-GFAP antiserum

Specificité: Specific for GFAP.

Réactivité croisée (Details): Reacts with: human (P14136), rat (P47819), mouse (P03995), chicken, zebrafish. Other species not tested yet.

Purification: antiserum

Immunogène: full-length recombinant human GFAP (UniProt Id: P14136)

Information d'application

Indications d'application: WB:1 : 1000 , IP:yes ICC:1 : 1000, IHC:1 : 500, IHC-P:1 : 1000 up to 1 : 5000, ELISA:

Commentaires:

WB: The polyclonal antibodies are more sensitive compared to the monoclonals. ELISA: Suitable as detector antibody for sandwich-ELISA as capture antibody (protocol for sandwich-ELISA).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

Conseil sur la manipulation: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Stock: -20 °C,4 °C

Stockage commentaire: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

Références pour anticorps anti-GFAP (ABIN1742363)

Hüttenrauch, Walter, Kaufmann, Weggen, Wirths: "Limited Effects of Prolonged Environmental Enrichment on the Pathology of 5XFAD Mice." dans: Molecular neurobiology, (2016) (PubMed).

Hüttenrauch, Baches, Gerth, Bayer, Weggen, Wirths: "Neprilysin deficiency alters the neuropathological and behavioral phenotype in the 5XFAD mouse model of Alzheimer's disease." dans: Journal of Alzheimer's disease : JAD, Vol. 44, Issue 4, pp. 1291-302, (2015) (PubMed).

Esposito, Drexler, Braganza, Doberentz, Grote, Widman, Drosten, Eis-Hübinger, Schoch, Elger, Becker, Niehusmann: "Large-scale analysis of viral nucleic acid spectrum in temporal lobe epilepsy biopsies." dans: Epilepsia, Vol. 56, Issue 2, pp. 234-43, (2015) (PubMed).

Cavanagh, Colby-Milley, Bouvier, Farso, Chabot, Quirion, Krantic: "βCTF-correlated burst of hippocampal TNFα occurs at a very early, pre-plaque stage in the TgCRND8 mouse model of Alzheimer's disease." dans: Journal of Alzheimer's disease : JAD, Vol. 36, Issue 2, pp. 233-8, (2013) (PubMed).

Kaeser-Woo, Younts, Yang, Zhou, Wu, Castillo, Südhof: "Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 23, pp. 9769-80, (2013) (PubMed).

Hillmann, Hahn, Schilling, Hoffmann, Demuth, Bulic, Schneider-Axmann, Bayer, Weggen, Wirths: "No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease." dans: Neurobiology of aging, Vol. 33, Issue 4, pp. 833.e39-50, (2012) (PubMed).

Ansorg, Witte, Urbach: "Age-dependent kinetics of dentate gyrus neurogenesis in the absence of cyclin D2." dans: BMC neuroscience, Vol. 13, pp. 46, (2012) (PubMed).

Araya-Callís, Hiemke, Abumaria, Flugge: "Chronic psychosocial stress and citalopram modulate the expression of the glial proteins GFAP and NDRG2 in the hippocampus." dans: Psychopharmacology, Vol. 224, Issue 1, pp. 209-22, (2012) (PubMed).

Kawano, Katsurabayashi, Kakazu, Yamashita, Kubo, Kubo, Okuda, Takasaki, Kubota, Mishima, Fujiwara, Harata, Iwasaki: "Long-term culture of astrocytes attenuates the readily releasable pool of synaptic vesicles." dans: PLoS ONE, Vol. 7, Issue 10, pp. e48034, (2012) (PubMed).

Ribic, Flügge, Schlumbohm, Mätz-Rensing, Walter, Fuchs: "Activity-dependent regulation of MHC class I expression in the developing primary visual cortex of the common marmoset monkey." dans: Behavioral and brain functions : BBF, Vol. 7, pp. 1, (2011) (PubMed).

Christensen, Schneider-Axmann, Lucassen, Bayer, Wirths: "Accumulation of intraneuronal Abeta correlates with ApoE4 genotype." dans: Acta neuropathologica, Vol. 119, Issue 5, pp. 555-66, (2010) (PubMed).

Ribic, Zhang, Schlumbohm, Mätz-Rensing, Uchanska-Ziegler, Flügge, Zhang, Walter, Fuchs: "Neuronal MHC class I molecules are involved in excitatory synaptic transmission at the hippocampal mossy fiber synapses of marmoset monkeys." dans: Cellular and molecular neurobiology, Vol. 30, Issue 6, pp. 827-39, (2010) (PubMed).

Wirths, Erck, Martens, Harmeier, Geumann, Jawhar, Kumar, Multhaup, Walter, Ingelsson, Degerman-Gunnarsson, Kalimo, Huitinga, Lannfelt, Bayer: "Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis." dans: The Journal of biological chemistry, Vol. 285, Issue 53, pp. 41517-24, (2010) (PubMed).

Détails sur GFAP

Antigène: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Autre désignation: GFAP

Sujet:

Synonyms: Glial fibrillary acidic protein, Neuroinflamm-Astrocyt

Antigen Information: GFAP is an astrocyte-specific type-III intermediate filament protein

UniProt: P14136