GFAP anticorps

N° du produit ABIN1742363

13+ publications sont disponibles pour ce produit. L’anticorps anti-GFAP Polyclonal produit chez le Lapin a été validé pour WB, IHC, ICC, IP et IHC (p). Il convient pour la détection de GFAP dans des échantillons provenant de Humain, Rat, Souris, Poulet et Poisson zèbre (Danio rerio). }

Aperçu rapide pour GFAP anticorps (ABIN1742363)

Antigène: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reactivité: Humain, Rat, Souris, Poulet, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFAP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GFAP anticorps

Fonction: Rabbit anti-GFAP antiserum

Specificité: Specific for GFAP.

Réactivité croisée (Details): Reacts with: human (P14136), rat (P47819), mouse (P03995), chicken, zebrafish. Other species not tested yet.

Purification: antiserum

Immunogène: full-length recombinant human GFAP (UniProt Id: P14136)

Information d'application

Indications d'application: WB:1 : 1000 , IP:yes ICC:1 : 1000, IHC:1 : 500, IHC-P:1 : 1000 up to 1 : 5000, ELISA:

Commentaires:

WB: The polyclonal antibodies are more sensitive compared to the monoclonals. ELISA: Suitable as detector antibody for sandwich-ELISA as capture antibody (protocol for sandwich-ELISA).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

Conseil sur la manipulation: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Stock: -20 °C,4 °C

Stockage commentaire: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

Références pour anticorps anti-GFAP (ABIN1742363)

Hüttenrauch, Walter, Kaufmann, Weggen, Wirths: "Limited Effects of Prolonged Environmental Enrichment on the Pathology of 5XFAD Mice." dans: Molecular neurobiology, (2016) (PubMed).

Hüttenrauch, Baches, Gerth, Bayer, Weggen, Wirths: "Neprilysin deficiency alters the neuropathological and behavioral phenotype in the 5XFAD mouse model of Alzheimer's disease." dans: Journal of Alzheimer's disease : JAD, Vol. 44, Issue 4, pp. 1291-302, (2015) (PubMed).

Esposito, Drexler, Braganza, Doberentz, Grote, Widman, Drosten, Eis-Hübinger, Schoch, Elger, Becker, Niehusmann: "Large-scale analysis of viral nucleic acid spectrum in temporal lobe epilepsy biopsies." dans: Epilepsia, Vol. 56, Issue 2, pp. 234-43, (2015) (PubMed).

Cavanagh, Colby-Milley, Bouvier, Farso, Chabot, Quirion, Krantic: "βCTF-correlated burst of hippocampal TNFα occurs at a very early, pre-plaque stage in the TgCRND8 mouse model of Alzheimer's disease." dans: Journal of Alzheimer's disease : JAD, Vol. 36, Issue 2, pp. 233-8, (2013) (PubMed).

Kaeser-Woo, Younts, Yang, Zhou, Wu, Castillo, Südhof: "Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 23, pp. 9769-80, (2013) (PubMed).

Hillmann, Hahn, Schilling, Hoffmann, Demuth, Bulic, Schneider-Axmann, Bayer, Weggen, Wirths: "No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease." dans: Neurobiology of aging, Vol. 33, Issue 4, pp. 833.e39-50, (2012) (PubMed).

Ansorg, Witte, Urbach: "Age-dependent kinetics of dentate gyrus neurogenesis in the absence of cyclin D2." dans: BMC neuroscience, Vol. 13, pp. 46, (2012) (PubMed).

Araya-Callís, Hiemke, Abumaria, Flugge: "Chronic psychosocial stress and citalopram modulate the expression of the glial proteins GFAP and NDRG2 in the hippocampus." dans: Psychopharmacology, Vol. 224, Issue 1, pp. 209-22, (2012) (PubMed).

Kawano, Katsurabayashi, Kakazu, Yamashita, Kubo, Kubo, Okuda, Takasaki, Kubota, Mishima, Fujiwara, Harata, Iwasaki: "Long-term culture of astrocytes attenuates the readily releasable pool of synaptic vesicles." dans: PLoS ONE, Vol. 7, Issue 10, pp. e48034, (2012) (PubMed).

Ribic, Flügge, Schlumbohm, Mätz-Rensing, Walter, Fuchs: "Activity-dependent regulation of MHC class I expression in the developing primary visual cortex of the common marmoset monkey." dans: Behavioral and brain functions : BBF, Vol. 7, pp. 1, (2011) (PubMed).

Christensen, Schneider-Axmann, Lucassen, Bayer, Wirths: "Accumulation of intraneuronal Abeta correlates with ApoE4 genotype." dans: Acta neuropathologica, Vol. 119, Issue 5, pp. 555-66, (2010) (PubMed).

Ribic, Zhang, Schlumbohm, Mätz-Rensing, Uchanska-Ziegler, Flügge, Zhang, Walter, Fuchs: "Neuronal MHC class I molecules are involved in excitatory synaptic transmission at the hippocampal mossy fiber synapses of marmoset monkeys." dans: Cellular and molecular neurobiology, Vol. 30, Issue 6, pp. 827-39, (2010) (PubMed).

Wirths, Erck, Martens, Harmeier, Geumann, Jawhar, Kumar, Multhaup, Walter, Ingelsson, Degerman-Gunnarsson, Kalimo, Huitinga, Lannfelt, Bayer: "Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis." dans: The Journal of biological chemistry, Vol. 285, Issue 53, pp. 41517-24, (2010) (PubMed).

Détails sur GFAP

Antigène: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Autre désignation: GFAP

Sujet:

Synonyms: Glial fibrillary acidic protein, Neuroinflamm-Astrocyt

Antigen Information: GFAP is an astrocyte-specific type-III intermediate filament protein

UniProt: P14136