LRRC32 anticorps (AA 296-308)

N° du produit ABIN1742450

L’anticorps Souris Monoclonal anti-LRRC32 a été validé pour FACS. Il convient pour détecter LRRC32 dans des échantillons de Humain. Il y a 3+ publications disponibles.

Aperçu rapide pour LRRC32 anticorps (AA 296-308) (ABIN1742450)

Antigène: LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LRRC32 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: 227G6

Détail du produit anti-LRRC32 anticorps

Épitope: AA 296-308

Specificité: Specific for GARP.

Immunogène: Synthetic peptide (aa 296-308 of human GARP) coupled to KLH via N-terminal added cysteine.

Isotype: IgG3

Information d'application

Indications d'application: WB: not recommended

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: For reconstitution add 100µl H2O to get a 1mg/ml solution in PBS.

Buffer: PBS. Azide was added before lyophilization.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Stock: -20 °C

Stockage commentaire: Reconstitute and aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized.

Références pour anticorps anti-LRRC32 (ABIN1742450)

Cuende, Liénart, Dedobbeleer, van der Woning, De Boeck, Stockis, Huygens, Colau, Somja, Delvenne, Hannon, Baron, Dumoutier, Renauld, De Haard, Saunders, Coulie, Lucas: "Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo." dans: Science translational medicine, Vol. 7, Issue 284, pp. 284ra56, (2015) (PubMed).

Rappl, Pabst, Riemann, Schmidt, Wickenhauser, Schütte, Hombach, Seliger, Grohé, Abken: "Regulatory T cells with reduced repressor capacities are extensively amplified in pulmonary sarcoid lesions and sustain granuloma formation." dans: Clinical immunology (Orlando, Fla.), Vol. 140, Issue 1, pp. 71-83, (2011) (PubMed).

Probst-Kepper, Geffers, Kröger, Viegas, Erck, Hecht, Lünsdorf, Roubin, Moharregh-Khiabani, Wagner, Ocklenburg, Jeron, Garritsen, Arstila, Kekäläinen, Balling, Hauser, Buer, Weiss: "GARP: a key receptor controlling FOXP3 in human regulatory T cells." dans: Journal of cellular and molecular medicine, Vol. 13, Issue 9B, pp. 3343-57, (2010) (PubMed).

Détails sur LRRC32

Antigène: LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

Autre désignation: GARP

Sujet: Synonyms: LRRC 32

Pathways: Activated T Cell Proliferation