CCR4 anticorps

N° du produit ABIN179723

L’anticorps Souris Monoclonal anti-CCR4 a été validé pour FACS et cELISA. Il convient pour détecter CCR4 dans des échantillons de Humain.

Aperçu rapide pour CCR4 anticorps (ABIN179723)

Antigène: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCR4 est non-conjugé

Application: Flow Cytometry (FACS), Cell-ELISA (cELISA)

Clone: KH-4F5

Détail du produit anti-CCR4 anticorps

Specificité: Anti-human CCR4

Purification: Protein G

Immunogène: immunisation with human CCR4 peptide

Isotype: IgG2a

Information d'application

Indications d'application: Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Commentaires:

Synonyms: CC chemokine receptor 4

Restrictions: For Research Use only

Stockage

Concentration: 2 mg/mL

Buffer: PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C

Stockage commentaire: short term: 2 °C - 8 °C, long term: -20 °C

Détails sur CCR4

Antigène: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Autre désignation: CCR4

Sujet: CCR4 (CC chemokine receptor 4) molecule belongs to the rhodopsin family of G-protein-coupled receptors. Chemokine receptors are membrane bound molecules composed of 7-transmembrane domains and coupled to G-proteins. CCR4 binds the chemokines CCL17 (TARC) and CCL22 (MDC) and is highly expressed in most single-positive CD4(+) thymocytes especially in TH2- and regulatory T-cells. It plays a central role in T cell migration to the thymus, T cell maturation and education. CCR4 is often up-regulated in inflammation and cause conformational changes that trigger intracellular signaling pathways.

UniProt: P51679