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Complement C4c anticorps

Cet anticorps anti-Complement C4c est un anticorps Souris Monoclonal détectant Complement C4c dans WB, IHC, FACS, ELISA, IHC (fro) et IHC (p). Adapté pour Humain.
N° du produit ABIN1804101

Aperçu rapide pour Complement C4c anticorps (ABIN1804101)

Antigène

Complement C4c (C4c) (Complement Component C4c (C4c))

Reactivité

Humain

Hôte

  • 12
  • 3
  • 1
Souris

Clonalité

  • 13
  • 3
Monoclonal

Conjugué

  • 8
  • 4
  • 1
  • 1
  • 1
  • 1
Cet anticorp Complement C4c est non-conjugé

Application

  • 11
  • 9
  • 7
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

10-12
  • Marque

    IHC-plus™

    Specificité

    Recognizes complement component 4c (C4c). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b's alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonization and activation of the classical pathway. iC4b is further degraded into the inactive fragments C4d and C4c. C4c consists of two a-chain fragments, alpha 4 (13 kD) and alpha 3 (25 kD) linked to a beta chain through disulphide bridges and a gamma chain. It is expressed in the blood plasma. Binds both C4c and C4 and so is not suitable for all ELISA applications.

    Purification

    Protein A purified from ascites

    Immunogène

    Purified human C4c.

    Isotype

    IgG1
  • Indications d'application

    Approved: ELISA, Flo, IHC, IHC-Fr, IHC-P (10 μg/mL), WB

    Usage: ELISA: Binds both C4c and C4 and so is not suitable for all ELISA applications.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Borate buffered saline, 0.09 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Aliquot to avoid repeated freezing and thawing. Store undiluted.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
  • Antigène

    Complement C4c (C4c) (Complement Component C4c (C4c))

    Autre désignation

    Complement C4c
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