L’anticorps anti-FeLV Envelope Glycoprotein Monoclonal Souris est utilisé pour la détection de FeLV Envelope Glycoprotein dans des échantillons de Feline Leukemia Virus (FeLV). Il a été validé pour IHC (p), IP et WB.
Immunohistochemistry on paraffin sections. Immunoprecipitation. Western Blot: 1: 2,000, detects band/s of approximately 15 kDa and 25 kDa under reducingconditions. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0mg/mL
Buffer
PBS, pH 7.2 containing 0.05 % Sodium Azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Date de péremption
12 months
Antigène
FeLV Envelope Glycoprotein
Classe de substances
Viral Protein
Sujet
Persistent infection of cats with the oncoretrovirus FeLV can result in the non-neoplastic condition known as FeLV-associated enteritis (FAE). Studies have shown strong expression of the major FeLV proteins p15e and gp70 in intestinal crypt epithelial cells of cats with FAE, compared to FeLV-positive cats without intestinal alterations, thereby suggesting a pathogenic role for these envelope proteins/precursors in FAE.Synonyms: Feline leukemia virus env, gp70, p15E