Interleukin 17a anticorps
Aperçu rapide pour Interleukin 17a anticorps (ABIN181032)
Antigène
Voir toutes Interleukin 17a (IL17A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognises mouse Interleukin 17.
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Attributs du produit
- Synonyms: IL-17A, IL17, IL-17, CTLA8, CTLA-8, Cytotoxic T-lymphocyte-associated antigen 8
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Purification
- Purified
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Immunogène
- Recombinant mouse IL-17 expressed in E. coli
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Isotype
- IgG1
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Indications d'application
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Borate buffered saline, pH 8.2
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Stock
- -20 °C
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Stockage commentaire
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Store the antibody in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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Autre désignation
- Interleukin-17A (IL17A)
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Sujet
- Interleukin 17 is a 32 kDa disulfide-linked homodimer consisting of two 136 amino acid chains, which belongs to the IL-17 family (classified as IL-17A to IL-17F), and signals through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17
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ID gène
- 16171
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UniProt
- Q62386
Antigène
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