EBV anticorps

N° du produit ABIN181081

Cet anticorps Rat Monoclonal détecte spécifiquement EBV dans WB et IHC (p). Il présente une réactivité avec des échantillons de Epstein-Barr Virus (EBV).

Aperçu rapide pour EBV anticorps (ABIN181081)

Antigène: EBV (Epstein-Barr Virus (EBV))

Reactivité: Epstein-Barr Virus (EBV)

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp EBV est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 15F9

Détail du produit anti-EBV anticorps

Attributs du produit: Synonyms: HHV4, Epstein Barr Virus LMP2A

Purification: Affinity Chromatography on Protein G

Immunogène: Bacterial TrpE-LMP2A fusion protein. Spleen cells from immunised Lou/c rats were fusedwith cells of the P3X63. Ag8. 653 myeloma cell line.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1/100 - 1/1000. Immunohistochemistry on paraffin sections: This product requires antigen retrieval usingheat treatment methods prior to staining of paraffin sections. Sodium citrate buffer pH 6.0is recommended for this purpose.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur EBV

Antigène: EBV (Epstein-Barr Virus (EBV))

Autre désignation: Epstein Barr Virus / EBV

Classe de substances: Virus

Sujet: EBV is a human herpesvirus, which is associated with conditions such as Hodgkins disease and Burkitts Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.Synonyms: HHV-4, HHV4