BMP7 anticorps

N° du produit ABIN181552

Détail du produit anti-BMP7 anticorps

Antigène: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP7 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Specificité: Detects BMP7.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography using an immobilized Human BMP7 matrix.

Immunogène: CHO cell derived recombinant highly pure (>98%) Human BMP-7.

Information d'application

Indications d'application: Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of Human BMP7 (100 ng/mL), a concentration of 0.40-0.60 μg/mL of this BMP7 antibody is required. Sandwich ELISA: To detect Human BMP7 by Sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.5-2.0 μg/mL is required. The antigen affinity purified BMP7 antibody, inconjunction with Biotinylated antibody anti-Human BMP7 antibody (ABIN181549 orABIN181550) as a Detection antibody, allows the detection of at least 0.2-0.4 ng/well ofrecombinant Human BMP-7. Western Blot: To detect Humnan BMP-7 by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant Hunan BMP-7 is 1.5-3.0 ng/lane, under either reducingor non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.

Date de péremption: 6 months

Détails sur BMP7

Antigène: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Autre désignation: BMP7 (BMP7 Produits)

Synonymes: anticorps bmp-7, anticorps bmp7, anticorps op-1, anticorps BMP7, anticorps zgc:153025, anticorps OP-1, anticorps OP1, anticorps BMP-7, anticorps fb83f09, anticorps wu:fb83f09, anticorps bone morphogenetic protein 7, anticorps bone morphogenetic protein 7, gene 1 L homeolog, anticorps bone morphogenetic protein 7b, anticorps bone morphogenetic protein 7, gene 2 L homeolog, anticorps bone morphogenetic protein 7a, anticorps BMP7, anticorps bmp7.1.L, anticorps LOC100136282, anticorps bmp7b, anticorps Bmp7, anticorps LOC100008826, anticorps bmp7.2.L, anticorps bmp7a

Sujet: Bone Morphogenetic Protein 7 (BMP7), also known as osteogenic protein 1 (OP1), is produced from a DNA sequence encoding the human BMP2 signal peptide and human BMP2 propeptide (amino acid residues 1 to 282) fused to the human BMP7 mature subunit (amino acid residues 293 to 431). Mature human BMP7, generated after the proteolytic removal of the signal peptide and the propeptide, is a disulfide linked homodimeric protein, comprised of two 139 amino acid residue subunits. Bone Morphogenetic Proteins (BMP) are members of the TGF beta superfamily of cytokines that affect bone and cartilage formation. Similar to other TGF beta family proteins, BMPs are highly conserved across animal species.Synonyms: BMP-7, Bone morphogenetic protein 7, OP1, Osteogenic protein 1

ID gène: 655

NCBI Accession: NP_001710

UniProt: P18075

Pathways: Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance