CMA1 anticorps

N° du produit ABIN181829

L’anticorps Souris Monoclonal anti-CMA1 a été validé pour WB, IHC (p), EIA et IHC (fro). Il convient pour détecter CMA1 dans des échantillons de Humain.

Aperçu rapide pour CMA1 anticorps (ABIN181829)

Antigène: CMA1 (Chymase 1, Mast Cell (CMA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CMA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: CC1

Détail du produit anti-CMA1 anticorps

Specificité: This antibody binds to mast cell chymase, it may be used to detect mast cells in routinely fixed tissues, and has been used to study the distribution of mast cells in skin, synovium, lung and heart. Binding of this antibody to chymase is not reduced in the presence of heparin, suggesting that the antibody does not bind to the heparin-binding domain of chymase.

Purification: Affinity Chromatography on Protein G.

Immunogène: Purified human skin chymase. Spleen cells from immunised BALB/c mice were fused with cells of the P3/NSI/I.Ag4.1 mouse myeloma cell line.

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western Blot. Immunohistochemistry on frozen sections: 1/500 - 1/1000, This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Recommended Positive Control: Skin
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CMA1

Antigène: CMA1 (Chymase 1, Mast Cell (CMA1))

Autre désignation: Mast Cell Chymase

Sujet: Mast Cell Chymase is an important marker of mast cells and also an important mediator of inflammation.Synonyms: Alpha-chymase, CMA1, CYH, CYM, Mast cell protease I

ID gène: 1215

NCBI Accession: NP_001827

UniProt: P23946

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis