CMA1 anticorps
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- Antigène Voir toutes CMA1 Anticorps
- CMA1 (Chymase 1, Mast Cell (CMA1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CMA1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- This antibody binds to mast cell chymase, it may be used to detect mast cells in routinely fixed tissues, and has been used to study the distribution of mast cells in skin, synovium, lung and heart. Binding of this antibody to chymase is not reduced in the presence of heparin, suggesting that the antibody does not bind to the heparin-binding domain of chymase.
- Purification
- Affinity Chromatography on Protein G.
- Immunogène
- Purified human skin chymase. Spleen cells from immunised BALB/c mice were fused with cells of the P3/NSI/I.Ag4.1 mouse myeloma cell line.
- Clone
- CC1
- Isotype
- IgG1
- Top Product
- Discover our top product CMA1 Anticorps primaire
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- Indications d'application
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ELISA. Western Blot. Immunohistochemistry on frozen sections: 1/500 - 1/1000, This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Recommended Positive Control: Skin
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- CMA1 (Chymase 1, Mast Cell (CMA1))
- Autre désignation
- Mast Cell Chymase (CMA1 Produits)
- Synonymes
- anticorps CYH, anticorps MCT1, anticorps chymase, anticorps MMCP-5, anticorps Mcp-5, anticorps Mcp5, anticorps Mcpt5, anticorps MCP3P, anticorps CMA1, anticorps Chymase, anticorps chymase 1, anticorps chymase 1, mast cell, anticorps chymase-like, anticorps CMA1, anticorps Cma1, anticorps LOC100008644
- Sujet
- Mast Cell Chymase is an important marker of mast cells and also an important mediator of inflammation.Synonyms: Alpha-chymase, CMA1, CYH, CYM, Mast cell protease I
- ID gène
- 1215
- NCBI Accession
- NP_001827
- UniProt
- P23946
- Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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