TREM2 anticorps (PE)
Aperçu rapide pour TREM2 anticorps (PE) (ABIN1819128)
Antigène
Voir toutes TREM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes Triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Stimulation of TREM-2 with clone 78.18 enhances multinucleated osteoclast formation in vitro. Clone 78.18 may also be used to block TREM-2 on pre-osteoclasts to inhibit the formation of multinuclear osteoclasts and to inhibit bone resorption by mature osteoclasts.
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Purification
- Protein G purified
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Immunogène
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Mouse TREM-2 Fc fusion protein.
Type of Immunogen: Fusion protein -
Isotype
- IgG1
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Indications d'application
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Approved: Flo
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Commentaires
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Target Species of Antibody: Mouse
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- 1 mL sterile distilled water
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide, 1 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze. Protect from light.
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Stock
- 4 °C
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Stockage commentaire
- Store at 4°C. Do not freeze. Protect from light.
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- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
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Autre désignation
- TREM2 / TREM-2
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Sujet
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Name/Gene ID: TREM2
Synonyms: TREM2, Trem2b, TREM-2, Trem2a, Trem2c -
ID gène
- 54209
Antigène
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