CD300a anticorps (PE)

N° du produit ABIN1819155

Cet anticorps anti-CD300a est un anticorps Souris Monoclonal détectant CD300a dans FACS. Adapté pour Humain.

Aperçu rapide pour CD300a anticorps (PE) (ABIN1819155)

Antigène: CD300a (CD300A)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD300a est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: P192

Détail du produit anti-CD300a anticorps (PE)

Specificité: Recognizes human CD300a, otherwise known as IRp60 (inhibitory receptor protein 60), a 60kD transmembrane glycoprotein expressed by natural killer cells (NK), T and B cell subsets, monocytes, neutrophils, macrophages, granulocytes, dendritic cells (DC) and mast cells. Studies have shown that the cross-linking of CD300a on NK results in a down-regulation of their cytolytic activity, whilst cross-linking of CD300a on mast cells, inhibits IgE-induced degranulation and SCF-mediated survival. Furthermore, cross-linking of CD300a on the surface of eosinophils has been shown to significantly inhibit their survival, chemotaxis and activation in response to certain inflammatory cytokines, whilst eosinophil-derived MBP (major basic protein) and EDN (neurotoxin), can down-regulate CD300a expression on mast cells in vitro.

Purification: Protein G purified

Immunogène: Polyclonal population of NK cells.

Type of Immunogen: Cells

Isotype: IgG2a

Information d'application

Indications d'application: Approved: Flo

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Reconstitute with 1 mL distilled water.

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze. Protect from light.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze. Protect from light.

Détails sur CD300a

Antigène: CD300a (CD300A)

Autre désignation: CD300A

Sujet: Name/Gene ID: CD300A

Synonyms: CD300A, CD300a antigen, CD300a molecule, CMRF35-like molecule 8, CMRF35-H, CMRF35-H9, CLM-8, CMRF35H9, IGSF12, Inhibitory receptor protein 60, IRC2, IRC1, NK inhibitory receptor, CMRF-35-H9, CMRF-35H, CMRF35H, IRC1a, IRp60, Leukocyte membrane antigen

ID gène: 11314

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process