SIGLEC7 anticorps

N° du produit ABIN1819168

Cet anticorps Souris Monoclonal détecte spécifiquement SIGLEC7 dans WB, ELISA, FACS, IP, Func et DNA Mic. Il présente une réactivité envers Humain, Macaque rhésus et Singe.

Aperçu rapide pour SIGLEC7 anticorps (ABIN1819168)

Antigène: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Reactivité: Humain, Macaque rhésus, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIGLEC7 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), DNA Microscopy (DNA Mic)

Clone: S7-7

Détail du produit anti-SIGLEC7 anticorps

Specificité: Recognizes human Sialic acid-binding Ig-like lectin 7, otherwise known as CD328, a putative adhesion molecule and member of the Ig superfamily, predominantly expressed by both resting and activated natural killer (NK) cells, and also at lower levels by monocytes, granulocytes, monocyte-derived macrophages and dendritic cells, and a small population of CD8+ memory T cells. Classified as a CD33-related Siglec, Siglec-7 preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid, and acts as a novel inhibitory receptor for NK cells, mediating the inhibition of NK cell cytotoxicity, and implicated in the regulation of NK cell and T cell activation, and hematopoiesis. Clone S7.7 is a blocking antibody see for details, and has been shown to recognize Siglec-7 in Rhesus monkey see for details.

Purification: Protein G purified

niveau d'endotoxine: Low Endotoxin

Immunogène: Siglec-7 3T3 transfected cells.

Type of Immunogen: Cells

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, Flo, Func, IP, WB

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur SIGLEC7

Antigène: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Autre désignation: SIGLEC7 / CD328

Sujet: Name/Gene ID: SIGLEC7
Family: Immunoglobulin

Synonyms: SIGLEC7, AIRM-1, AIRM1, CD328 antigen, CDw328, CD328, D-siglec, QA79, SIGLEC-7, QA79 membrane protein

ID gène: 27036