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DC-SIGN/CD209 anticorps (FITC)

L’anticorps Souris Monoclonal anti-DC-SIGN/CD209 a été validé pour FACS. Il convient pour détecter DC-SIGN/CD209 dans des échantillons de Humain.
N° du produit ABIN181973

Aperçu rapide pour DC-SIGN/CD209 anticorps (FITC) (ABIN181973)

Antigène

Voir toutes DC-SIGN/CD209 (CD209) Anticorps
DC-SIGN/CD209 (CD209) (CD209)

Reactivité

  • 132
  • 27
  • 20
  • 1
  • 1
Humain

Hôte

  • 82
  • 64
  • 5
  • 1
Souris

Clonalité

  • 79
  • 73
Monoclonal

Conjugué

  • 66
  • 11
  • 11
  • 8
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp DC-SIGN/CD209 est conjugé à/à la FITC

Application

  • 73
  • 56
  • 50
  • 34
  • 28
  • 19
  • 13
  • 8
  • 7
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Clone

MR-1
  • Specificité

    This antibody recognises DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45 kDa C-type lectin that binds ICAM-3 which is also known as CD209. Clone MR-1 is reported to partially block the functional activity of DC-SIGN. We recommend the use of SM2219LE for this purpose.

    Purification

    Affinity chromatography on Protein G

    Immunogène

    Immature myeloid monocyte-derived dendritic cells (MDDCs). Spleen cells from immunised Balb/c mice were fused with cells of the Mouse SP2/0-Ag14 myeloma cell line.

    Isotype

    IgG1
  • Indications d'application

    Flow Cytometry: Neat - 1/5, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    0.1 mg/mL

    Buffer

    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    DC-SIGN/CD209 (CD209) (CD209)

    Autre désignation

    CD209 / DC-SIGN

    Sujet

    CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

    ID gène

    9606

    UniProt

    Q9NNX6
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