DC-SIGN/CD209 anticorps

N° du produit ABIN181975

Cet anticorps Souris Monoclonal détecte spécifiquement DC-SIGN/CD209 dans FACS et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour DC-SIGN/CD209 anticorps (ABIN181975)

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DC-SIGN/CD209 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: MR-1

Détail du produit anti-DC-SIGN/CD209 anticorps

Specificité: This antibody recognises DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN, CD209), a 45 kDa C-type lectin that binds ICAM-3.

Purification: Protein G affinity chtromatography

Immunogène: Immature myeloid monocyte-derived dendritic cells (MDDCs)

Isotype: IgG1

Information d'application

Indications d'application: Immunofluorescence. Flow cytometry: 1/50 - 1/100. Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Clone MR-1 is reported to partially block the functional activity of DC-SIGN (see ref. 2).

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DC-SIGN/CD209

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Autre désignation: CD209 / DC-SIGN

Sujet: CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

ID gène: 9606

UniProt: Q9NNX6