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DC-SIGN/CD209 anticorps (PE)

L’anticorps Souris Monoclonal anti-DC-SIGN/CD209 a été validé pour FACS. Il convient pour détecter DC-SIGN/CD209 dans des échantillons de Humain.
N° du produit ABIN181976

Aperçu rapide pour DC-SIGN/CD209 anticorps (PE) (ABIN181976)

Antigène

Voir toutes DC-SIGN/CD209 (CD209) Anticorps
DC-SIGN/CD209 (CD209) (CD209)

Reactivité

  • 129
  • 26
  • 20
  • 1
  • 1
Humain

Hôte

  • 82
  • 59
  • 4
  • 1
  • 1
  • 1
Souris

Clonalité

  • 75
  • 73
Monoclonal

Conjugué

  • 64
  • 11
  • 10
  • 8
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp DC-SIGN/CD209 est conjugé à/à la PE

Application

  • 73
  • 56
  • 52
  • 34
  • 28
  • 19
  • 13
  • 8
  • 7
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Clone

MR-1
  • Specificité

    This antibody recognises human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45 kDa C-type lectin that binds ICAM-3 which is also known as CD209. Clone MR-1 is reported to partially block the functional activity of DC-SIGN. We recommend the use of SM2219LE for this purpose.

    Purification

    Affinity Chromatography on Protein G.

    Immunogène

    Immature myeloid monocyte-derived dendritic cells (MDDCs). Spleen cells from immunised Balb/c mice were fused with cells of the Mouse SP2/0-Ag14 myeloma cell line.

    Isotype

    IgG1
  • Indications d'application

    Flow Cytometry (Neat-1/10): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Reconstitution

    Restore with 1 mL distilled water

    Concentration

    0.1 mg/mL

    Buffer

    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    This product is photosensitive and should be protected from light

    Stock

    4 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • Antigène

    DC-SIGN/CD209 (CD209) (CD209)

    Autre désignation

    CD209 / DC-SIGN

    Sujet

    CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

    ID gène

    9606

    UniProt

    Q9NNX6
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