LAMP2 anticorps (FITC)

N° du produit ABIN1819854

Cet anticorps anti-LAMP2 est un anticorps Souris Monoclonal détectant LAMP2 dans WB, FACS, IP et IF. Adapté pour Humain, Chien et Vison.

Aperçu rapide pour LAMP2 anticorps (FITC) (ABIN1819854)

Antigène: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Reactivité: Humain, Chien, Vison

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LAMP2 est conjugé à/à la FITC

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: AC17

Détail du produit anti-LAMP2 anticorps (FITC)

Specificité: Recognizes canine CD107b, otherwise known as LAMP-2, a 95kD heavily-glycosylated type I integral lysosomal glycoprotein, shown to share high N-terminal amino acid sequence homology with human, mouse and rat CD107b. Lysosomes are membrane-bound organelles found within the cytoplasm of most cells, which contain hydrolytic enzymes and act as the major compartment for heterophagic and autophagic digestion. Members of the lysosomal-associated membrane protein family (LAMPS) are believed to play an important role in protecting the lysosomal membrane from protease degradation and are involved in lectin-mediated cell adhesion. Evidence shows that CD107b is involved in the lysosomal uptake of cytosolic proteins and the endocytic pathway and human studies have revealed a correlation between the level of surface expression of CD107b on tumor cells and their metastatic potential. Clone AC17 has been shown as suitable for use in Electron Microscopy.

Aucune reactivité croisée: Souris, Rat (Rattus)

Purification: Protein G purified

Immunogène: MDCK (Madin-Darby Canine Kidney) cells.

Type of Immunogen: Cells

Isotype: IgG1

Information d'application

Indications d'application: Approved: Flo (1:1), IF, IP, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Dog

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. Protect from light.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.

Détails sur LAMP2

Antigène: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Autre désignation: LAMP2 / CD107b

Sujet: Name/Gene ID: LAMP2
Family: Cancer

Synonyms: LAMP2, CD107b, CD107b antigen, LAMPB, LGP110, LAMP-2

ID gène: 3920

Pathways: Autophagy