Nitrotyrosine anticorps
Aperçu rapide pour Nitrotyrosine anticorps (ABIN1820112)
Antigène
Voir toutes Nitrotyrosine AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes both free and protein-bound nitrotyrosine (Tyr-NO2), including human serum nitro albumin, nitro insulin and nitro haemoglobin. Nitrotyrosine arises from the nitration of protein tyrosine residues, by reactive nitrogen species such as peroxynitrite and nitrogen dioxide, and can be used as a measure of NO-dependent oxidative stress and cell damage. Increased levels of nitrotyrosine are detectable in various pathological conditions including atherosclerosis, rheumatoid arthritis, cardiovascular disease, lung cancer and vasculitis. The specificity of the antibody as determined by competition ELISA is: Nitrotyrosine:95 % of inhibition, Tyrosine:0 % of inhibition, Nitrotryptophan:4 % of inhibition, Aminotyrosine:0 % of inhibition, Phosphotyrosine:2 % of inhibition, Chlorotyrosine:3 % of inhibition,.
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Purification
- Protein A purified
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Immunogène
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Protein-bound Nitrotyrosine.
Type of Immunogen: Hapten -
Isotype
- IgG1
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Indications d'application
- Approved: ELISA, IP (1 μg/mL), WB (0.1 μg/mL)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Nitrotyrosine
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Classe de substances
- Chemical
Antigène
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