TREM2 anticorps

N° du produit ABIN1820125

Cet anticorps Rat Monoclonal détecte spécifiquement TREM2 dans FACS et Func. Il présente une réactivité envers Souris.

Aperçu rapide pour TREM2 anticorps (ABIN1820125)

Antigène: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp TREM2 est non-conjugé

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 78-18

Détail du produit anti-TREM2 anticorps

Specificité: Recognizes Triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Stimulation of TREM-2 with clone 78.18 enhances multinucleated osteoclast formation in vitro. Clone 78.18 may also be used to block TREM-2 on pre-osteoclasts to inhibit the formation of multinuclear osteoclasts and to inhibit bone resorption by mature osteoclasts.

Purification: Protein G purified

niveau d'endotoxine: Low Endotoxin

Immunogène: Mouse TREM-2 Fc fusion protein.

Type of Immunogen: Fusion protein

Isotype: IgG1

Information d'application

Indications d'application: Approved: Flo (1:25 - 1:200), Func

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur TREM2

Antigène: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Autre désignation: TREM2 / TREM-2

Sujet: Name/Gene ID: TREM2

Synonyms: TREM2, Trem2b, TREM-2, Trem2a, Trem2c

ID gène: 54209