TREM2 anticorps
Aperçu rapide pour TREM2 anticorps (ABIN6796398)
Antigène
Voir toutes TREM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes Triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Stimulation of TREM-2 with clone 78.18 enhances multinucleated osteoclast formation in vitro. Clone 78.18 may also be used to block TREM-2 on pre-osteoclasts to inhibit the formation of multinuclear osteoclasts and to inhibit bone resorption by mature osteoclasts.
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Purification
- Protein G purified
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Immunogène
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Mouse TREM-2 Fc fusion protein.
Type of Immunogen: Fusion protein -
Isotype
- IgG1
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Indications d'application
- Approved: Flo (1:25 - 1:200)
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Commentaires
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Target Species of Antibody: Mouse
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
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Autre désignation
- TREM2 / TREM-2
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Sujet
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Name/Gene ID: TREM2
Synonyms: TREM2, Trem2b, TREM-2, Trem2a, Trem2c -
ID gène
- 54209
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UniProt
- Q9NZC2
Antigène
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