Sialoadhesin/CD169 anticorps (FITC)

N° du produit ABIN1820283

Cet anticorps anti-Sialoadhesin/CD169 est un anticorps Rat Monoclonal détectant Sialoadhesin/CD169 dans FACS et IF. Adapté pour Souris.

Aperçu rapide pour Sialoadhesin/CD169 anticorps (FITC) (ABIN1820283)

Antigène: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Sialoadhesin/CD169 est conjugé à/à la FITC

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: MOMA-1

Détail du produit anti-Sialoadhesin/CD169 anticorps (FITC)

Specificité: Specific for CD169, also known as sialoadhesin. The antibody reacts with a subpopulation of mature resident tissue macrophages. No reactivity is seen with dendritic cells, peritoneal resident macrophages, peritoneal exudate cells or blood cells. Distinct macrophage subpopulations of lymphoid organs express the antigen. In the spleen, they are localized at the marginal sinus forming a ring around the periarteriolar lymphocyte sheath and follicular areas at the inner side of marginal zones. In lymph nodes, they are localized in the sinusoids and medullary cords but not within follicular areas or paracortex. In Peyer's patches they are localized in the interfollicular areas at the serosal side. Kupffer cells in the liver can be clearly stained by MOMA-1, although antigen expression is weaker than that seen in splenic macrophages. No MOMA-1 positive macrophages were found in the thymus. Reactivity was also negative in following organs tested so far (kidney, brain, skin). In non-lymphoid organs, the antigen is only found on a macrophage subpopulation in the lamina propria of the villi of the small intestine.

Aucune reactivité croisée: Humain, Rat (Rattus)

Purification: Protein G purified

Immunogène: Stromal (reticular) elements from spleen.

Isotype: IgG2a

Information d'application

Indications d'application: Approved: Flo (1:1), IF

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. Protect from light.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.

Détails sur Sialoadhesin/CD169

Antigène: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Autre désignation: SIGLEC1 / CD169 / Sialoadhesin

Sujet: Name/Gene ID: SIGLEC1
Family: Immunoglobulin

Synonyms: SIGLEC1, CD169, CD169 antigen, SIGLEC-1, Sialoadhesin, SN, DJ1009E24.1

ID gène: 6614