NEFH anticorps

N° du produit ABIN1834898

Détail du produit anti-NEFH anticorps

Antigène: NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Reactivité: Humain, Rat, Souris, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEFH est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Recognizes bovine intermediate 200 kD Neurofilament H (NFH), a 1026 amino acid ~200 kD protein involved in the maintenance of neuronal integrity. Neurofilaments are a major component of the cellular cytoskeleton, acting as the most abundant support for the axon cytoplasm. They exist as three neurofilament proteins: 68/70 kD (NFL) 160 kD (NFM) and 200 kD (NFH), which are expressed in both the central and peripheral nervous systems. Although typically expressed by neurons, neurofilaments are also expressed by neuroblastomas, neuromas, gangliogliomas, ganglioneuromas, and ganglioneuroblastomas, as well as paragangliomas, carcinoids, skin neuroendocrine carcinomas, and oat cell carcinomas of the lung. Defects in NFH are responsible for susceptibility to the neurodegenerative disorder amyotrophic lateral sclerosis (ALS) which affects upper and lower motor neurons, and results in fatal paralysis.

Purification: Purified

Immunogène: GST-tagged bovine NFH recombinant protein.

Type of Immunogen: Recombinant protein

Isotype: IgG

Information d'application

Indications d'application: Approved: IHC, IHC-P (1 μg/mL), WB (0.1 μg/mL)

Commentaires:

Target Species of Antibody: Bovine

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-glycine buffered saline, sodium chloride, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur NEFH

Antigène: NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Autre désignation: NEFH / NF-H (NEFH Produits)

Synonymes: anticorps NF-H, anticorps NF200, anticorps Nfh, anticorps mKIAA0845, anticorps NFH, anticorps NEFH, anticorps neurofilament heavy polypeptide, anticorps neurofilament, heavy polypeptide, anticorps neurofilament heavy, anticorps MCYG_06231, anticorps Nefh, anticorps NEFH

Sujet: Name/Gene ID: NEFH

Synonyms: NEFH, 200 kDa neurofilament protein, KIAA0845, NFH, NF-H

ID gène: 4744