Asialoglycoprotein Receptor 1 anticorps
Aperçu rapide pour Asialoglycoprotein Receptor 1 anticorps (ABIN1839609)
Antigène
Voir toutes Asialoglycoprotein Receptor 1 (ASGR1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The asialoglycoprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kD) which mediates binding, internalization and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i. e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediates the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed.
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Purification
- Purified
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Immunogène
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Crude rat liver membrane extracts.
Type of Immunogen: Membrane extract -
Isotype
- IgG1
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Indications d'application
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Approved: Flo, IHC, IHC-Fr, WB
Usage: For use in Western blot, non-reducing conditions are required. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.02 % sodium azide, 0.1 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 4°C.
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- Asialoglycoprotein Receptor 1 (ASGR1)
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Autre désignation
- ASGR1 / ASGPR
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Sujet
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Name/Gene ID: ASGR1
Synonyms: ASGR1, ASGPR1, ASGPR, ASGPR 1, Asialoglycoprotein receptor 1, Hepatic lectin H1, HL-1, ASGP-R 1, CLEC4H1 -
ID gène
- 432
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UniProt
- P07306
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Pathways
- Thyroid Hormone Synthesis
Antigène
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