Hexosaminidase A anticorps

N° du produit ABIN1846273

Détail du produit anti-Hexosaminidase A anticorps

Antigène: Hexosaminidase A (HEXA)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Hexosaminidase A est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human HEXA expressed in E. coli.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Détails sur Hexosaminidase A

Antigène: Hexosaminidase A (HEXA)

Autre désignation: HEXA (HEXA Produits)

Synonymes: anticorps TSD, anticorps fc04h11, anticorps wu:fc04h11, anticorps wu:fv09f06, anticorps si:dkey-35i22.2, anticorps HEXA, anticorps Hex-1, anticorps zgc:112084, anticorps hexosaminidase subunit alpha, anticorps hexosaminidase B (beta polypeptide), anticorps CUGBP Elav-like family member 6, anticorps hexosaminidase A, anticorps hexosaminidase A (alpha polypeptide), anticorps beta-hexosaminidase subunit alpha-like, anticorps HEXA, anticorps hexb, anticorps CELF6, anticorps Hexa, anticorps hexa, anticorps LOC100228061

Sujet: This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines.Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes.Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases.Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses.Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

Poids moléculaire: 60.7 kDa

ID gène: 3073, 15211, 300757

Pathways: Sensory Perception of Sound, Glycosaminoglycan Metabolic Process