STXBP1 anticorps (C-Term)

N° du produit ABIN185107

Cet anticorps Chèvre Polyclonal détecte spécifiquement STXBP1 dans WB, ELISA et IHC. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour STXBP1 anticorps (C-Term) (ABIN185107)

Antigène: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp STXBP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Classe de qualité: Verified

Détail du produit anti-STXBP1 anticorps

Épitope: C-Term

Fonction: MUNC18 / STXBP1 (isoform a)

Séquence: SRVSFEDQAP TME

Specificité: This antibody is expected to recognize isoform a (NP_003156.1).

Réactivité croisée: Humain, Souris

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogène: Peptide with sequence C-SRVSFEDQAPTME, from the C Terminus of the protein sequence according to NP_003156.1.

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry: Paraffin embedded Human Brain (Cortex). Recommended concentration: 5 μg/mL.

Western Blot: Approx 70-75 kDa band observed in Human Cerebellum lysates (calculated MW of 68.7 kDa according to Human NP_003156.1). Recommended concentration: 0.1-0.3 μg/mL. Primary incubation 1 hour at room temperature.

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Références pour anticorps anti-STXBP1 (ABIN185107)

Meijer, Cijsouw, Toonen, Verhage: "Synaptic Effects of Munc18-1 Alternative Splicing in Excitatory Hippocampal Neurons." dans: PLoS ONE, Vol. 10, Issue 9, pp. e0138950, (2016) (PubMed).

Détails sur STXBP1

Antigène: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Autre désignation: STXBP1

Sujet: STXBP1, MUNC18-1, UNC18, hUNC18, syntaxin binding protein 1, Hunc18, rbSec1, syntaxin-binding protein 1, RP11-56D16.3, EIEE4, FLJ37475, RBSEC1

ID gène: 6812, 20910

NCBI Accession: NP_003156

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport