Desmoglein 3 anticorps

N° du produit ABIN187349

L’anticorps anti-Desmoglein 3 Monoclonal Souris est utilisé pour la détection de Desmoglein 3 dans des échantillons de Humain. Il a été validé pour WB, IF, IP et IHC (p).

Aperçu rapide pour Desmoglein 3 anticorps (ABIN187349)

Antigène: Desmoglein 3 (DSG3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmoglein 3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5G11

Détail du produit anti-Desmoglein 3 anticorps

Specificité: Reacts with the 140 kDa desmoglein 3 protein. Does not cross-react with desmoglein 1 or desmoglein 2. The antibody does not inhibit biological activity of desmoglein 3. Species Reactivity: Human. Others not tested.

Stérilité: 0.2 μm filtered

Isotype: IgG1

Information d'application

Indications d'application: Immunofluorescence: Use at a 1:10 dilution Immunohistochemistry (paraffin embedded sections) Immunoprecipitation Western blot: Use at a 1:10 dilution The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 1 mL at 100 µg/mL of 0.2 µm filtered antibody solution in PBS containing 0.1% protein stabilizer and 0.02% sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur Desmoglein 3

Antigène: Desmoglein 3 (DSG3)

Autre désignation: Desmoglein-3

Sujet: Desmoglein 3 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 3 is synthesized in both the basal and the lower suprabasal compartments.