CD51/CD61 anticorps

N° du produit ABIN187672

Cet anticorps Souris Monoclonal détecte spécifiquement CD51/CD61 dans FACS, IP et IHC (fro). Il présente une réactivité envers Humain et Poulet.

Aperçu rapide pour CD51/CD61 anticorps (ABIN187672)

Antigène: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Reactivité: Humain, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD51/CD61 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 23C6

Détail du produit anti-CD51/CD61 anticorps

Specificité: Recognizes 110/90 kDa antigen known as the alpha chain of the vitronectin receptor (VNR). Clone 23C6 reacts with osteoclasts, placenta, melanoma cell lines, some epithelia cells. It reacts weakly with platelets. Clone 23C6 recognises the intact complex formed between the CD51 and CD61 molecules (av and b3 integrins). This complex binds vitronectin at the RGD sequence and can also bind von Willebrand factor, fibrinogen, thrombospondin, fibronectin, osteopontin and collagen. Species Reactivity: Human and chicken. Does not cross react with porcine, lapine or bovine tissues.

Immunogène: Human osteoclastoma tissue

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: Working dilution of 1:40 -1:80. Recommended second antibodies: FITC-conjugated F(ab')2 rabbit anti-mouse IgG Immunohistochemistry -Frozen sections: Working dilution of 1:50-1:100. Clone 23C6 shows no reactivity on fixed tissues. Immunoprecipitation The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Product: 200 µg purified IgG at approximately 1 mg/mL in PBS at pH 7.4 with 0.09% sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur CD51/CD61

Antigène: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Autre désignation: CD51/CD61 Complex