LPAR3 anticorps (C-Term)
Aperçu rapide pour LPAR3 anticorps (C-Term) (ABIN187789)
Antigène
Voir toutes LPAR3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- Reacts with EDG-7. Species Reactivity: Human, other species not tested.
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Stérilité
- 0.2 μm filtered
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Immunogène
- Synthetic peptide derived from the C-terminal of the EDG-7 receptor.
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Indications d'application
- Western Blot: Use at 5-10 µg/ml using a human EDG-7 receptor transfected cell line. The optimal dilution for a specific application should be determined by the researcher.
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Restrictions
- For Research Use only
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Buffer
- Rabbit polyclonal antibody against human EDG-7 (CT). Available at 100 µg/100 µl in PBS with 0.08% sodium azide. Purification: Sterile filtered at 0.2 µm.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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- LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))
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Autre désignation
- EDG-7 / LPAR3
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Sujet
- EDG-7 belongs to a family of G-protein coupled receptors whose lignads are lysophospholipids. The ligand for EDG-7 sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-7 is expressed in prostate as well as other tissues.
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Pathways
- Regulation of Cell Size
Antigène
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