ATP2A1/SERCA1 anticorps (C-Term)

N° du produit ABIN1881089

Il existe 3+ publications pour ce produit. L’anticorps anti-ATP2A1/SERCA1 Polyclonal Lapin est utilisé pour la détection de ATP2A1/SERCA1 dans des échantillons de Humain. Il a été validé pour WB, IHC (p) et FACS.

Aperçu rapide pour ATP2A1/SERCA1 anticorps (C-Term) (ABIN1881089)

Antigène: ATP2A1/SERCA1 (ATP2A1) (ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP2A1/SERCA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB25882

Détail du produit anti-ATP2A1/SERCA1 anticorps

Épitope: AA 974-1001, C-Term

Homologie: Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ATP2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 974-1001 amino acids from the C-terminal region of human ATP2A1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ATP2A1/SERCA1 (ABIN1881089)

Salanova, Schiffl, Blottner: "Atypical fast SERCA1a protein expression in slow myofibers and differential S-nitrosylation prevented by exercise during long term bed rest." dans: Histochemistry and cell biology, Vol. 132, Issue 4, pp. 383-94, (2009) (PubMed).

Chami, Oulès, Szabadkai, Tacine, Rizzuto, Paterlini-Bréchot: "Role of SERCA1 truncated isoform in the proapoptotic calcium transfer from ER to mitochondria during ER stress." dans: Molecular cell, Vol. 32, Issue 5, pp. 641-51, (2008) (PubMed).

Thorleifsson, Walters, Gudbjartsson, Steinthorsdottir, Sulem, Helgadottir, Styrkarsdottir, Gretarsdottir, Thorlacius, Jonsdottir, Jonsdottir, Olafsdottir, Olafsdottir, Jonsson, Jonsson et al.: "Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity...." dans: Nature genetics, Vol. 41, Issue 1, pp. 18-24, (2008) (PubMed).

Détails sur ATP2A1/SERCA1

Antigène: ATP2A1/SERCA1 (ATP2A1) (ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1))

Autre désignation: ATP2A1

Sujet: ATP2A1 encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction.

Poids moléculaire: 110252

NCBI Accession: NP_004311, NP_775293

UniProt: O14983

Pathways: Ribonucleoside Biosynthetic Process