BCL9L anticorps (N-Term)

N° du produit ABIN1881110

Il existe 4+ publications pour ce produit. L’anticorps anti-BCL9L Polyclonal Lapin est utilisé pour la détection de BCL9L dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour BCL9L anticorps (N-Term) (ABIN1881110)

Antigène: BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL9L est non-conjugé

Application: Western Blotting (WB)

Clone: RB41624

Détail du produit anti-BCL9L anticorps

Épitope: AA 147-176, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This BCL9L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the N-terminal region of human BCL9L.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-BCL9L (ABIN1881110)

Miller, Rutherford, Johnson, Fiedler, Bienz: "Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor." dans: Journal of molecular biology, Vol. 401, Issue 5, pp. 969-84, (2010) (PubMed).

Fritzmann, Morkel, Besser, Budczies, Kosel, Brembeck, Stein, Fichtner, Schlag, Birchmeier: "A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential." dans: Gastroenterology, Vol. 137, Issue 1, pp. 165-75, (2009) (PubMed).

Sampietro, Dahlberg, Cho, Hinds, Kimelman, Xu: "Crystal structure of a beta-catenin/BCL9/Tcf4 complex." dans: Molecular cell, Vol. 24, Issue 2, pp. 293-300, (2006) (PubMed).

Brembeck, Schwarz-Romond, Bakkers, Wilhelm, Hammerschmidt, Birchmeier: "Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions." dans: Genes & development, Vol. 18, Issue 18, pp. 2225-30, (2004) (PubMed).

Détails sur BCL9L

Antigène: BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))

Autre désignation: BCL9L

Sujet: Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity).

Poids moléculaire: 157129

NCBI Accession: NP_872363

UniProt: Q86UU0

Pathways: Stem Cell Maintenance