BLMH anticorps (AA 212-242)

N° du produit ABIN1881113

L’anticorps Lapin Polyclonal anti-BLMH a été validé pour WB et IHC (p). Il convient pour détecter BLMH dans des échantillons de Humain, Rat et Souris. Il y a 2+ publications disponibles.

Aperçu rapide pour BLMH anticorps (AA 212-242) (ABIN1881113)

Antigène: BLMH (Bleomycin Hydrolase (BLMH))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BLMH est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BLMH anticorps

Épitope: AA 212-242

Homologie: Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This BLMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-242 amino acids from the Central region of human BLMH.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-BLMH (ABIN1881113)

Ferrando, Velasco, Campo, Lopez-Otin: "Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance." dans: Cancer research, Vol. 56, Issue 8, pp. 1746-50, (1996) (PubMed).

Brömme, Rossi, Smeekens, Anderson, Payan: "Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization." dans: Biochemistry, Vol. 35, Issue 21, pp. 6706-14, (1996) (PubMed).

Détails sur BLMH

Antigène: BLMH (Bleomycin Hydrolase (BLMH))

Autre désignation: BLMH

Sujet: The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity).

Poids moléculaire: 52562

NCBI Accession: NP_000377

UniProt: Q13867