BRSK1 anticorps (AA 355-384)

N° du produit ABIN1881121

Cet anticorps Lapin Polyclonal détecte spécifiquement BRSK1 dans WB. Il présente une réactivité envers Souris et a été mentionné dans 3+ publications.

Aperçu rapide pour BRSK1 anticorps (AA 355-384) (ABIN1881121)

Antigène: BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRSK1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB40234

Détail du produit anti-BRSK1 anticorps

Épitope: AA 355-384

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This BRSK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 355-384 amino acids from the Central region of human BRSK1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-BRSK1 (ABIN1881121)

Alvarado-Kristensson, Rodríguez, Silió, Valpuesta, Carrera: "SADB phosphorylation of gamma-tubulin regulates centrosome duplication." dans: Nature cell biology, Vol. 11, Issue 9, pp. 1081-92, (2009) (PubMed).

Fogarty, Hardie: "C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest." dans: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 77-84, (2008) (PubMed).

Bright, Carling, Thornton: "Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation." dans: The Journal of biological chemistry, Vol. 283, Issue 22, pp. 14946-54, (2008) (PubMed).

Détails sur BRSK1

Antigène: BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

Autre désignation: BRSK1

Sujet: Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV-or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.

Poids moléculaire: 85087

NCBI Accession: NP_115806

UniProt: Q8TDC3