CCDC6 anticorps (N-Term)

N° du produit ABIN1881146

Il existe 4+ publications pour ce produit. L’anticorps anti-CCDC6 Polyclonal Lapin est utilisé pour la détection de CCDC6 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour CCDC6 anticorps (N-Term) (ABIN1881146)

Antigène: CCDC6 (Coiled-Coil Domain Containing 6 (CCDC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC6 est non-conjugé

Application: Western Blotting (WB)

Clone: RB40538

Détail du produit anti-CCDC6 anticorps

Épitope: AA 54-82, N-Term

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CCDC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the N-terminal region of human CCDC6.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CCDC6 (ABIN1881146)

Leone, Mansueto, Pierantoni, Tornincasa, Merolla, Cerrato, Santoro, Grieco, Scaloni, Celetti, Fusco: "CCDC6 represses CREB1 activity by recruiting histone deacetylase 1 and protein phosphatase 1." dans: Oncogene, Vol. 29, Issue 30, pp. 4341-51, (2010) (PubMed).

Richardson, Gujral, Peng, Asa, Mulligan: "Transcript level modulates the inherent oncogenicity of RET/PTC oncoproteins." dans: Cancer research, Vol. 69, Issue 11, pp. 4861-9, (2009) (PubMed).

Jazdzewski, Murray, Franssila, Jarzab, Schoenberg, de la Chapelle: "Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 20, pp. 7269-74, (2008) (PubMed).

Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." dans: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, (2007) (PubMed).

Détails sur CCDC6

Antigène: CCDC6 (Coiled-Coil Domain Containing 6 (CCDC6))

Autre désignation: CCDC6

Sujet: This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.

Poids moléculaire: 53291

NCBI Accession: NP_005427

UniProt: Q16204