CXCR5 anticorps (N-Term)

N° du produit ABIN1881245

Détail du produit anti-CXCR5 anticorps

Antigène: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Épitope: AA 1-30, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR5 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CXCR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CXCR5.

Clone: RB41684

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CXCR5 (ABIN1881245)

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Lee, Shiao, Wu, Chen, Hsu, Tsai, Tsai: "Serum BLC/CXCL13 concentrations and renal expression of CXCL13/CXCR5 in patients with systemic lupus erythematosus and lupus nephritis." dans: The Journal of rheumatology, Vol. 37, Issue 1, pp. 45-52, (2009) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." dans: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Détails sur CXCR5

Antigène: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Autre désignation: CXCR5 (CXCR5 Produits)

Synonymes: anticorps BLR1, anticorps CRL1, anticorps CD185, anticorps MDR15, anticorps Blr1, anticorps CXC-R5, anticorps CXCR-5, anticorps Gpcr6, anticorps NLR, anticorps C-X-C motif chemokine receptor 5, anticorps chemokine (C-X-C motif) receptor 5, anticorps CXCR5, anticorps Cxcr5

Sujet: This gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist.

Poids moléculaire: 41955

NCBI Accession: NP_001707, NP_116743

UniProt: P32302